TRAVEL: 30 MILES
Sample local wines at some of the Front Range's 20 wineries (coloradowine.com), including award-winning Viogniers at Boulder's Bookcliff Vineyard tasting room (bookcliffvineyards.com), on Pearl Street, dry, rich merlots at the Boulder Creek Winery (bouldercreekwine.com), and honey wine at Redstone Meadery (redstonemeadery.com). Then pass out at Boulder's Briar Rose Bed and Breakfast, where the next day you can relax in the meditation room or enjoy an organic breakfast before heading home (doubles from $149; briarrosebb.com).
TRAVEL: 70 MILES
Cast a line for the kind of fish that keep fly-fishermen up at night. Nursed back from the brink of extinction, greenback cutthroat trout are vibrant Front Range natives now fishable in Rocky Mountain National Park (nps.gov/romo). Hike or ride a horse in with Wild Basin Outfitters (from $250 per day; wildbasinoutfitters.com) to Odessa Lake, where cuts salivate over Parachute Adams. Later, spend the night at the 90-year-old Baldpate Inn (doubles from $100, including breakfast; baldpateinn.com).
TRAVEL: 164 MILES
Soak in the buff at Valley View Hot Springs, the San Luis Valley's secluded wilderness resort. The natural pools have seen heavy traffic since at least 1873, when local iron miners came here to bathe. These days, visitors come to experience the tranquillity of one of the state's unofficial spiritual centers. Call in advance to reserve a tent site, historic cabin, or room in the communal lodge (from $52, including use of hot springs; olt.org).
TRAVEL: 228 MILES
Boat the narrow channels of the 22-mile-long Blue Mesa Reservoir, Colorado's largest body of water, with Alan Bernholtz, Crested Butte mayor and owner of Crested Butte Mountain Guides. CBMG leads overnight sea-kayaking trips (camping gear provided) on the reservoir, taking you past eerie volcanic formations in the high desert ($240; crestedbutteguides.com).