Cyclomundo's six-day, five-night ride from Lake Geneva (1,220 feet) to l'Alpe d'Huez (6,100 feet) is both beautiful and brawny. Over the course of the 224-mile trip, cyclists tackle some of the hairiest climbs in the French Alps—including Tour de France regulars Colombière and Galibier—taking in views of Mont Blanc and Lake Geneva en route. Cyclomundo offers a self-guided option—lodging, meals, a GPS, maps, and a bike mechanic are provided, but a guide is not. So if you need motivation, take the fully outfitted option, which comes with the same provisions but also a guide, a support vehicle, and a peloton of up to 15 other travelers. $910 self-guided; $1,250 guided; cyclomundo.com.