Andros is the largest of the Bahamian islands—at 2,300 square miles, it's nearly four times the size of Oahu—but with just 7,600 locals, it's also the wildest. Off the eastern shore sits the third-largest barrier reef on earth; on the west, world-class bonefishing flats. But here's the thing: Andros is one of the most accessible islands in the Caribbean. After a three-hour flight from New York (or an hour from Miami) and a 15-minute puddle-jumper from Nassau on Flamingo Air (flamingoairbah.com), your feet will be dangling in blue water. Set up shop at Swain's Cay Bonefish Resort, a new Bahamian-owned joint on the east coast. It has local fishing guides and kayaks and snorkel gear aplenty (packages from $300 per night for two; swainscayresort.com). Book Mangrove Villa 1—you can practically cast for bones from the patio. Then paddle among mangroves, snorkel with bottlenose dolphins on the Andros Barrier Reef, or take a fishing trip on the island's west side with fourth-generation guide Ralph Moxey. No matter which adventure you choose, dinner is Swain's Cay's lobster-grouper-and-conch platter.