Hormone Blocks Marijuana Buzz

The World Wonders Why This is a Good Thing


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On Thursday, a group of French researchers isolated a hormone that blocks the high you get from weed.

What? Why?

“Their discovery could lead to new approaches to treating marijuana intoxication and addiction,” reports the journal Science, in which the study appears.

The steroid hormone, pregnenolone, a molecule generated by the brain, behaves like a natural defense mechanism against the negative impacts of cannabis in animals (such as cognitive loss and laziness). This could be useful in preventing addiction, researchers at the French Institute of Health and Medical Research (INSERM) said.

“We hope to be able to start clinical trials in people in a year to a year and a half,” INSERM researcher Pier Vincenzo Piazza told AFP.

So far in the study, the role of the hormone has only been identified in rats, using equivalent doses of cocaine, morphine, nicotine, alcohol, and marijuana for comparison.